Holy Hand Grenade plays out on a 5-reel and 4-row grid featuring 26 paylines. Players match monastery-themed symbols across the reels while random Superspinners add win multipliers to passing payouts. The Holy Hand Grenade symbol can land at any time to transform random paytable symbols.

Triggering the free spins bonus expands the grid to 6x5 with 52 paylines. Active grenade symbols remain sticky during the feature to amplify subsequent explosions and award extra spins.